Chinese scientists develop early diagnosis of liver cancer for hepatitis B carriers
2019-03-13 09:22 | xinhua

  Chinese scientists have designed a new screening method for hepatitis B carriers, to detect early-stage hepatocellular carcinoma (HCC), the most common type of primary liver cancer.

  The new method was developed by researchers from Cancer Hospital, Chinese Academy of Medical Sciences and Genetron Health, a biomedical company. Through a liquid biopsy that detects cell-free DNA somatic mutations in combination with protein markers, researchers can efficiently identify early-stage HCC cases of less than 3 cm.

  According to Yan Hai, one of the researchers, the method showed 100 percent sensitivity, 94 percent specificity and 17 percent positive predictive value in the validation cohort, proving it a feasible approach to identify early stage HCC.

  The research team will optimize this screening method through systematic research in a multi-center, large prospective cohort study, Yan said.

  After rigorous clinical validation, this method is expected to become a more convenient, non-invasive and standardized early screening program for liver cancer.

  The research was published in the U.S. journal Proceedings of the National Academy of Sciences.

  Links
Copyright©2013-2015,Secretariat for Cooperation between China and Central and Eastern European Countries
Address: No. 2, Chaoyangmen Nandajie, Chaoyang District, Beijing, 100701 FAX:86-10-65962554